School of Medicine

Wayne State University School of Medicine

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John Jacobs, M.D.
Professor, Wayne State University Otolaryngology
Research Educator track, full time
Program Director, Head and Neck Oncology Fellowship

Wayne State University School of Medicine
Deptartment of Otolaryngology
4201 St. Antoine
Detroit, MI  48201



Dr. John Jacobs was a Professor in the Department of Otolaryngology Head and Neck Surgery, Wayne State University, Detroit, Michigan.  He joined the department in 1980 after completing his residency in Otolaryngology at Barnes Hospital, Washington University School of Medicine in St. Louis, Missouri.   He trained with the internationally renown surgeon Dr. Joseph Ogura. Dr Ogura developed and popularized many of the current surgical techniques for preservation of the larynx. Dr. Jacobs was a Professor at Karmanos Cancer Institute since 1999, and an Adjunct Professor of the Radiation Oncology Department of Wayne State University since 1995. Following undergraduate training as a biomedical engineer Dr. Jacobs received an MD from Northwestern University School of Medicine, Chicago, Illinois in 1975.  

Dr. Jacobs had extensive experience in the combined modality management of the cancer patient. He was past chairman of both the surgery committee and head and neck surgical committee of the Radiation Therapy Oncology Group. He also served as trial chairman for many clinical trials involving both therapy and rehabilitation of the cancer patient and has been a funded investigator of the National Institute of Health.   

Dr Jacobs published extensively and was routinely invited to lecture both nationally and internationally. 

Awards & Honors

Best Doctors in America/Styleline Magazine 2009, 2013, 2014.  

Voted Detroit Super Doctors list 2014 

Invited member "Best Doctors InterConsultation Group" 2010  

Best Doctors in America/Styleline Magazine 2009. 

Voted Hour Detroits Top Docs 2008 and 2009.

Areas of Interest

Head and neck cancer
salivary gland cancer
thyroid cancer
combined modality treatment for head and neck cancer

Post Graduate Training

Northwestern University, Evanston, Illinois
B.S.S.E. (Biomedical Engineering), 1971

Northwestern University School of Medicine, Chicago, Illinois
M.D., 1975

Joint Appointments
Professor, Karmanos Cancer Institute
Adjunct Professor, Radiation Oncology Department
Other Information

General Surgical Resident
Jewish Hospital
St. Louis, Missouri- 1975-1976

Otolaryngology Resident

Barnes Hospital/Washington University School of Medicine
St. Louis, Missouri

Chief Resident
Barnes Hospital

  • head and neck cancer
  • salivary gland cancer
  • thyroid cancer
  • combined modality treatment for head and neck cancer
Selected Publications

last 5 years:

Hurst NJ, Jacobs JR, et al:  Intratumoral Lymphatic Vessel Density as a Predictor of Progression-Free and Overall Survival in Locally Advanced Laryngeal/Hypopharyngeal Cancer. Head Neck. 2015 Jan 10. doi: 10.1002/hed.24011. [Epub ahead of print] PMID:25641342.

Jha N, Deshmukh S, Seikaly H, Jacobs J, et al:  Results of Quality of Life for Phase IINRG Oncology RTOG 0244 Study Using Submandibular Salivary Gland Transfer procedure for Prevention of Radiation-Induced Xerostomia in Head and Neck Cancer Patients.  Submitted to Int J of Rad Onc, Bio, Phy June 2015.

Chopra S, Kamdar D, Tulunay O, Marunick M, Kim H, Lin H, Jacobs J:  Factors Predictive of Severity of ORN of the Mandible.  Head & Neck, 2011 Nov;33(11):1600-5; online pub April 11, 2011.   Doi:10.1002/ned.21654. PMID:21484922.

Paximadis P, Kumar T, Yoo G, Lin H, Jacobs J, Sukari A, Kafri Z., Yoo, WS, Kim H: Addition of Concurrent Chemoradiation Improves Survival in Hypopharyngeal Cancer.   Int J Radiation Oncology Biol Phys 2012; 82(4):1515-1521.

Kafri Z, Heilbrun L, Sukari A, Yoo G, Jacobs J, Lin H, Mulrenan H, Smith D, Kucuk O: Phase II Study of Gemcitabine and Docetaxel Combination (GEMDOC) in Patients with Previously Treated Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck.  ISRN Oncology, vol. 2012, Article ID 159568, 6 pages, 2012. Doi:10.5401/2012/159568 

Ozgursoy O, Jacobs J:  The Necessity of Routine Ipsilateral Hemithyroidectomy during Laryngopharyngectomy for Piriform Sinus Cancer.   American Journal of Otolaryngology, September-October 2012, 33(5):p562.

Jha N, Jacobs J, et al: A phase II Study of Submandibular Gland Transfer Prior to Radiation for Prevention of Radiation-Induced Xerostomia in Head and Neck Cancer (RTOG 0244).  International Journal of Radiation Oncology, Biology,Physics, Oct 2012;84(2):437-42. Doi: 10.1016/j.ijrobp.2012.02/034.  Epub 2012 Apr. 27.

Jacobs J:  The Challenge and Opportunity of New Technology in Otolaryngology.   Editorial JOR-1-e105 accepted for publication in Journal of Otology & Rhinology 2012.


Margenthaler J, Jacobs J, Chopra S, et al:  Patient Surveillance after Cancer Treatment. 2nd Ed. Springer, 2011.

Book Chapters:

Chopra S, Jacobs J:  Follow-up of Carcinoma of the Upper Aerodigestive Tract- Counterpoint.  Patient Surveillance after Cancer Treatment 2nd Edn, Springer 2011. 


Tulunay OE, Jacobs JR:  Management of the Carotid Artery in Advanced Head and Neck Cancer.  Head & Neck Surgery 1st Edition, Jaypee Brothers, PP 1335-1341, 2009.